Cadmium cation increases the production and mRNA levels of insulin-like growth factor-binding protein-1 in HepG2.
نویسندگان
چکیده
The production of insulin-like growth factor-binding protein-1 (IGFBP-1) in HepG2 was increased by cadmium cation (Cd2+) at 3 microM, but not by other divalent cations. The mRNA level of IGFBP-1 was also increased by the administration of 3 microM of Cd(2+). These results suggest that Cd(2+) impacts the gene expression of IGFBP-1, which leads to production of IGFBP-1.
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ورودعنوان ژورنال:
- Bioscience, biotechnology, and biochemistry
دوره 71 5 شماره
صفحات -
تاریخ انتشار 2007